search for transcript abundance info 3-29-13

2014-08-29

azim58 - search for transcript abundance info 3-29-13

Scott H. What transcripts are found in a human cell? Genome Biology 2000;

Leveraging skewed transcript abundance by RNA-Seq
to increase the genomic depth of the tree of life

ref 29:

Mortazavi A, Williams BA, McCue K, Schaeffer L, Wold B (2008) Mapping and
quantifying mammalian transcriptomes by RNA-Seq. Nat Methods 5:621–628.

Using Poisson mixed-effects model to quantify transcript-level gene
expression in RNA-Seq.

related article
Landscape of transcription in human cells
-article found with this search term: high abundance of low copy

transcripts

-Assuming that 1–4 r.p.k.m. approximates to 1 copy per cell18, we find

that almost one-quarter of expressed protein-coding genes and 80% of
the detected lncRNAs are present in our samples in 1 or fewer copies
per cell.

distribution of transcript abundance