Sequence-Tagged Site STS portal 10-15-2014d1703
2015-01-13Sequence-Tagged Site STS portal 10-15-2014d1703
what does sts mean in a dna database?
sts = sequence-tagged site
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Sequence-Tagged Site (STS)
is a relatively short, easily PCR-amplified sequence (200 to 500 bp) which can be specifically amplified by PCR and detected in the presence of all other genomic sequences and whose location in the genome is mapped.
The STS concept was introduced by Olson et al (1989). In assessing the likely impact of the Polymerase Chain Reaction (PCR) on human genome research, they recognized that single-copy DNA sequences of known map location could serve as markers for genetic and physical mapping of genes along the chromosome.