Rota rod test 11-19-2014d0927
2015-04-28Rota rod test 11-19-2014d0927
rotarod portal
portal
rotarod performance test
The length of time that a given animal stays on this rotating rod is a measure of their balance, coordination, physical condition, and motor-planning.
- -q
pictures of our rotarod setup at CNIO
In the Bruno 2012 paper "Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer" they did the rotarod test in the following way
To evaluate the motor coordination and balance, mice were tested in a
Rota-Rod apparatus (model LE 8200); the measures score the latency
of fall, with a continuous acceleration protocol, from 4 to 40 rpm, for a
maximum of 60 s in three trials (Castelhano-Carlos et al, 2010). The
tightrope test was performed as described elsewhere (Ingram &
Reynolds, 1986; Matheu et al, 2007; Tomas-Loba et al, 2008).
Some papers
-The Rotarod Test: An Evaluation of Its Effectiveness in Assessing Motor Deficits Following Traumatic Brain Injury
--behind paywall; I requested from the CNIO library 12-15-2014d0953
--ROBERT J. HAMM, BRIAN R. PIKE, DIANNE M. O'DELL, BRUCE G. LYETH, and LARRY W. JENKINS. Journal of Neurotrauma. April 1994, 11(2): 187-196. doi:10.1089/neu.1994.11.187.
--http://online.liebertpub.com/doi/abs/10.1089/neu.1994.11.187
-The quantitative measurement of motor inco-ordination in naive mice using an accelerating rotarod
--behind paywall; I requested from the CNIO library 12-15-2014d0953
--B. J. JONES and D. J. ROBERTS
--Journal of Pharmacy and Pharmacology
--Volume 20, Issue 4, pages 302–304, April 1968