Preparation of a Linearized Vector by PCR

2015-01-13

azim58 - Preparation of a Linearized Vector by PCR


PrimeStar Max polymerase seems to work the best for vector linearization

see 11-27-12 Polymerase system test for polymerization
for initial test of polymerases for linearization

1 ng of template seems to work just fine
see 11-27-12 of notebook for an example


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Advantage HD can also be used, but doesn't seem to work as well

see
"C:\kurt\storage\CIM Research Folder\DR\2012\11-5-12\preparation of a
linearized vector by PCR 11-5-12.docx"

The In-Fusion SMARTer Directional cDNA Library Construction Kit
also has instructions for linearization.