Entropy Measures Quantify Global Splicing Disorders in Cancer 01-12-2014d0652
2015-01-13Entropy Measures Quantify Global Splicing Disorders in Cancer 01-12-2014d0652
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-alternative splicing entropy is significantly higher in 13 of 27 cancers compared to normal tissues of the same anatomical site.
-abberant splice forms
-the genes that present the highest entropy
gain are enriched in splicing factors.
- correlation between high proliferation signature and high entropy (correlation coefficient of 0.81)