BDE Seminar Presentation 3-27-12

2013-12-01

azim58 - BDE Seminar Presentation 3-27-12

I will talk about two topics in this presentation: the immunosignature
entropy topic as well as probing my tumor cDNA library if there is time.
Here are some presentations I will use as a reference for this
presentation:

"C:\kurt\storage\CIM Research
Folder\DR\2013\1-26-13\data_download\1920\Immunosignature Entropy Summary
3 3-2-12.ppt"

"C:\kurt\storage\CIM Research Folder\kwhittem\Presentations\2012\BDE
Seminar Presentation 3-27-12\Spring 2012 General Meeting 4-4-12.ppt"

Here is the scan from my notebook that I gave the presentation from.

"C:\kurt\storage\CIM Research Folder\kwhittem\Presentations\2012\BDE
Seminar Presentation 3-27-12\Immunosignature Entropy 3-27-12.pdf"

Comments or insights from audience during presentation (I can't remember
them all but here are a few)

what are the number of affinity and specificity (I should really find

a reference for the decrease in these traits)

what is a child, adolescent, and adult for a mouse
make sure to write natural log rather than log for the calculations

that I calculated that way

People commented that I could get the entropy over a time course to

see how it changes with time

Justin mentioned that I could purify antibodies against a specific

target and then see how that changes

I could also see the difference in entropy in a time course after

immunization for old and young

Tom brought up the issue that more jagged peaks seen on the higher

entropy old sera could indicate more specificity. . .hmmmm. . something
to think about
o one thought is that some of the old sharp peaks could be due to
left over antibodies that developed at a younger age perhaps? Not
sure. .

Afterward Cosmo told me about a book that looks quite interesting,

and he said it had a major impact on his life. He said the book is
called Linked and was written by Albert Lazlo Barbasi. The book also
talks about Alfred Rangy and Ero^s. He mentioned that Jieping Ye here
at ASU does work with brain type scans and is giving a talk in a few
days. This may relate to the increase in the distribution of neuron
connections.

Six Degrees

and
Bursts: The Hidden Pattern Behind Everything We Do

Here's an e-mail I sent to Cosmo about varying stimulation
Here's a followup e-mail to Johnny about the optimal entropy for life