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search for transcript abundance info 3-29-13
2014-08-29
azim58 - search for transcript abundance info 3-29-13 Scott H. What transcripts are found in a human cell? Genome Biology 2000; 1. Leveraging skewed transcript abundance by RNA-Seq to increase the genomic depth of the tree of life -ref 29: Mortazavi A, Williams BA, McCue K, Schaeffer L, Wold B (2008) Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods 5:621–628. -related article Using Poisson mixed-effects model to quantify transcript-level gene expression in RNA-Seq. -related article -Landscape of transcription in human cells --article found with this search term: high abundance of low copy transcripts --Assuming that 1–4 r.p.k.m. approximates to 1 copy per cell18, we find that almost one-quarter of expressed protein-coding genes and 80% of the detected lncRNAs are present in our samples in 1 or fewer copies per cell. distribution of transcript abundance
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