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Blasco publication text files 02-09-2014d0910
2014-02-09
POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia.txt The hallmarks of aging.txt p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes.txt TRF1 is a stem cell marker and is essential for the generation of induced pluripotent stem cells.txt Telomerase at the intersection of cancer and aging.txt Telomere Length and Telomerase Activity Impact the UV Sensitivity Syndrome Xeroderma Pigmentosum.txt A metabolic signature predicts biological age in mice.txt Short telomeres are frequent in hereditary breast tumors and are associated with high tumor grade.txt Telomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity.txt Interview: Fighting disease from the chromosome end.txt RAP1 protects from obesity through its extratelomeric role regulating gene expression.txt Localization-dependent and -independent roles of SLX4 in regulating telomeres.txt Personal omics profiling reveals dynamic molecular and medical phenotypes.txt A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division.txt Assessing cell and organ senescence biomarkers.txt Potential of telomerase activation in extending health span and longevity.txt 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response.txt Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion.txt Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres.txt Identification of novel pathways involved in the pathogenesis of human adamantinomatous craniopharyngioma.txt Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of Dyskeratosis congenita.txt Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer.txt Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases.txt Beyond average c potential for measurement of short telomeres.txt The Rate of Increase of Short Telomeres Predicts Longevity in Mammals.txt Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins.txt Aging by telomere loss can be reversed.txt Isolation and in vitro expansion of human colonic stem cells.txt Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes.txt Different telomere-length dynamics at the inner cell mass versus established embryonic stem (ES) cells.txt Genomic instability in iPS: time for a break.txt Telomeres in cancer and ageing.txt Suv4-20h Abrogation Enhances Telomere Elongation during Reprogramming and Confers a Higher Tumorigenic Potential to iPS Cells.txt The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder.txt Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites.txt TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice.txt BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping.txt p53 Prevents entry into mitosis with uncapped telomeres.txt ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase.txt SIRT1 contributes to telomere maintenance and augments global homologous recombination.txt Telomere rejuvenation during nuclear reprogramming.txt 2009 nobel prize in physiology or medicine: telomeres and telomerase.txt TERRA transcripts are bound by a complex array of RNA-binding proteins.txt Role of shelterin in cancer and aging.txt Chromatin regulation and non-coding RNAs at mammalian telomeres.txt The role of telomeres and telomerase in stem cell aging.txt Impact papers on aging in 2009.txt Telomeres and telomerase in adult stem cells and pluripotent embryonic stem cells.txt The Ink4/Arf locus is a barrier for iPS cell reprogramming.txt A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity.txt Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells.txt Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.txt Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations.txt A 'higher order' of telomere regulation: Telomere heterochromatin and telomeric RNAs.txt MSH2 deficiency abolishes the anticancer and pro-aging activity of short telomeres.txt Telomere Shortening in Neural Stem Cells Disrupts Neuronal Differentiation and Neuritogenesis.txt TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis.txt Telomere shortening and oxidative stress in aged macrophages results in impaired STAT5a phosphorylation.txt A p53-dependent response limits epidermal stem cell functionality and organismal size in mice with short telomeres.txt Genetic dissection of the mechanisms underlying telomere-associated diseases Impact of the TRF2 telomeric protein on mouse epidermal stem cells.txt
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