causes of aging portal 06-16-2014d2210

SENS
{
Cell loss and cell atrophy — Stem cells and tissue engineering
 Nuclear [epi]mutations — WILT, short for "Whole-body Interdiction of Lengthening of Telomeres"
 Mitochondrial mutations — Allotopic expression of 13 proteins
 Death-resistant cells — Targeted removal
 Extracellular crosslinks — AGE-breaking molecules and tissue engineering
 Extracellular aggregates — Stimulating of the immune system to clear out the aggregates
 Intracellular aggregates — Equipping the lysosome with enzymes capable of degrading the aggregates

}

Hallmarks of aging paper ([The Hallmarks of Aging])
{
Genomic instability
Telomere attrition
Epigenetic alterations
Loss of proteostasis
Deregulated nutrient sensing
Mitochondrial dysfunction
Cellular senescence
Stem cell exhaustion
Altered intercellular communication
}

My personal opinion of what is missing from the focus of general aging research
{
-entropy
-autoimmunity (keep the immune system on track and prevent autoimmunity)
-keeping cells healthy and happy through use and stimulation
}